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Nanoblade for Operations on Cells

Scientists of the University of California, Los Angeles, have created a nanoblade to perform operations on the cellular level.

It is reported that the device system generally includes a microscope, micro-pipette and laser. You can use it to extract mitochondria from cells and put them back.

It is known that mitochondrial mutations can provoke fatal diseases. DNA can be edited with the nanoblade and, as a consequence, some illnesses can be avoided.

The publication notes that a test of the new device has already been carried out. With the help of it, professionals were able to extract the nucleus from one cell and put them into another one. Then they decided to go a step further and experiment with cellular mitochondria.

Nanoblade creators are convinced that it will help in the fight against many infectious diseases. Earlier it was reported that doctors will deal with cancer by "nano-grenades".hi-tech microscope

The scientists have developed a "nano-grenade" that can deliver a drug directly into a cancer tumor and "explode" in it under the influence of the heat produced by cancer cells. The report about this was given at a conference on the fight against cancer in Liverpool, RIA Science.

"In our case, the thermal" check "is set to the temperature of 42 degrees of Celsius, which is only a couple of degrees higher than normal body temperature. Even though we checked the work of our "grenades" only in the laboratory, there is a range of ways to "warm up " cancerous cells in the patient's body, some of which are already used in medical practice," - said Costas Kostarelos from the University of Manchester.

Kostarelos and his colleagues have created their "thermal grenades" on the basis of the so-called liposomes - microscopic fluid balls surrounded by "nano-armour" that consist of synthetic fat molecules, which gradually disintegrate when ingested into the body.

Manchester’s doctors have changed the structure of the liposome in such a way that their stability is beginning to depend on the environment temperature.

If liquid remains colder than a certain point - 42 degrees in this case - then the fat globules are stable almost indefinitely. If they are heated to this point they break up almost immediately and release their contents.

As the researchers note, they have already conducted several tests on cancer cell cultures in the laboratory and on tumors transplanted into mice bodies, which confirmed the operation of "thermal grenades" and allowed Kostarelosa’s team to improve their "fighting" qualities.

In these experiments, scientists have successfully been able to eliminate cancer in the mice and extend their life using an antibody, which is capable of recognizing melanoma cells, skin cancer as a "stuffing" for the liposomes.

As the scientists hope, in the near future they could receive permission to continue the experiments and begin clinical trials of their "grenades".